Innate Immunity @ Tübingen
Interdisciplinary alliance of researchers in Tübingen

News


NCII conference date 2023 announced:

Save the date for 31 May - 02 June 2023


New joint publications:

BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity. J Exp Med. 2021;218(11):e20201656.

Bittner ZA, Liu X, Dickhöfer S, Kalbacher H, Bosch K, Andreeva L, Marcu A, Stevanovic S, Mangan M, Düwell, Lovotti M, Herster F, Löffler MW, Shankar S, Tapia-Abellán A, Wolz OO, Schilling NA, Kümmerle-Deschner J, Wagner  S, Delor A, Grimbacher B, Wu H, Latz E, Weber ANR.


NLRP3 Inflammasome Assembly in Neutrophils Is Supported by PAD4 and Promotes NETosis Under Sterile Conditions. Front Immunol. 2021; 12:683803.

Münzer P, Negro R, Fukui S, di Meglio L, Aymonnier K, Chu L, Cherpokova D, Gutch S, Sorvillo N, Shi L, Magupalli VG, Weber ANR, Scharf RE, Waterman CM, Wu H, Wagner DD.


Staphylococcus aureus Skin Colonization Is Enhanced by the Interaction of Neutrophil Extracellular Traps with Keratinocytes. J Invest Dermatol 2020;140(5):1054-1065.

Bitschar K, Staudenmaier L, Klink L, Focken J, Sauer B, Fehrenbacher B, Herster F, Bittner Z, Bleul L, Schaller M, Wolz C, Weber ANR, Peschel A, Schittek B.

 


Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis. Nat Commun 2020; 11(1):105.

Herster F, Bittner Z, Archer NK, Dickhöfer S, Eisel D, Eigenbrod T, Knorpp T, Schneiderhan-Marra N, Löffler MW, Kalbacher H, Vierbuchen T, Heine H, Miller LS, Hartl D, Freund L, Schäkel K, Heister M, Ghoreschi K, Weber ANR.


Platelets Aggregate With Neutrophils and Promote Skin Pathology in Psoriasis. Front Immunol. 2019

Herster F, Bittner Z, Codrea MC, Archer NK, Heister M, Löffler MW, Heumos S, Wegner J, Businger R, Schindler M, Stegner D, Schäkel K, Grabbe S, Ghoreschi K, Miller LS, Weber ANR.


A new synthetic toll-like receptor 1/2 ligand is an efficient adjuvant for peptide vaccination in a human volunteer. Immunother Cancer. 2019

Rammensee HG, Wiesmüller KH, Chandran PA, Zelba H, Rusch E, Gouttefangeas C, Kowalewski DJ, Di Marco M, Haen SP, Walz JS, Gloria YC, Bödder J, Schertel JM, Tunger A, Müller L, Kießler M, Wehner R, Schmitz M, Jakobi M, Schneiderhan-Marra N, Klein R, Laske K, Artzner K, Backert L, Schuster H, Schwenck J, Weber ANR, Pichler BJ, Kneilling M, la Fougère C, Forchhammer S, Metzler G, Bauer J, Weide B, Schippert W, Stevanović S, Löffler MW. 


Flagellin hypervariable region determines symbiotic properties of commensal Escherichia coli strains. PLoS Biol. 2019

Steimle A, Menz S, Bender A, Ball B, Weber ANR, Hagemann T, Lange A, Maerz JK, Parusel R, Michaelis L, Schäfer A, Yao H, Löw HC, Beier S, Tesfazgi Mebrhatu M, Gronbach K, Wagner S, Voehringer D, Schaller M, Fehrenbacher B, Autenrieth IB, Oelschlaeger TA, Frick JS


June 2019

CRC/TR 156 "The skin as sensor and effector organ orchestrating local and systemic immune response"

The DFG-funded CRC/TR156 "The skin as sensor and effector organ orchestrating local and systemic immune response" will be extended by another 4 years, from 2019-2023. Participating PIs from Tübingen are:

  • Stefan Hailfinger
  • Manfred Kneiling
  • Daniela Kramer
  • Dorothee Kretschmer
  • Andreas Peschel
  • Bernd Pichler
  • Martin Röcken
  • Birgit Schittek
  • Alexander Weber and
  • Christiane Wolz


To find out more about the CRC follow the link: CRC/TR 156.