Role of TLRs and other pattern recognition receptors in cancer and other diseases (Area C)

Finally, we are interested in the role of PRRs in complex human diseases, studying these receptors in both patient material as well as experimental in vivo models. This work is done in collaboration with clinicians at the University Hospital and several research networks the lab is part of (see Funding page). Current projects include the study of MyD88-IRAK2 signaling in the context of lymphoma, the role of NLRs in colorectal cancer progression, and the role of TLRs in psoriasis.